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Home - Products - Cell Cycle/DNA Damage - Integrin - RWJ 50271

RWJ 50271

CAS No. 162112-37-0

RWJ 50271 ( —— )

Catalog No. M22175 CAS No. 162112-37-0

RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RWJ 50271
  • Note
    Research use only, not for human use.
  • Brief Description
    RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).
  • Description
    RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Integrin
  • Recptor
    LFA-1/ICAM-1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    162112-37-0
  • Formula Weight
    410.41
  • Molecular Formula
    C18H17F3N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:230 mg/mL?(487.32 mM), Need ultrasonic
  • SMILES
    Cc1c(cnn1-c1nc(cs1)-c1cccc(c1)C(F)(F)F)C(=O)NCCCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sanfilippo PJ, et al. Novel thiazole based heterocycles as inhibitors of LFA-1/ICAM-1 mediated cell adhesion. J Med Chem. 1995 Mar 31;38(7):1057-9.
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